Yves Boucher

Cancer Biologist | Retired Associate Professor of Radiation Oncology, Harvard Medical School

Dr. Yves Boucher is a cancer biologist with expertise in the tumor microenvironment, drug delivery, experimental therapeutics, and translational oncology. His research is mainly focused on elucidating how the tumor microenvironment (e.g. poor vascular supply) impedes the delivery and effectiveness of small and large therapeutics in solid tumors, and identifying adjuncts that normalize the tumor microenvironment and improve the efficacy of immunotherapy or cytotoxic treatment. Dr. Boucher’s group has also determined how stromal modifiers (e.g., anti-angiogenic agents) combined with cytotoxic agents affect the immune and non-immune tumor microenvironment and clinical outcomes in patients with breast and pancreatic cancer.

Dr. Boucher received his PhD in experimental pathology from Laval University and acquired post-doctoral experience at Carnegie Mellon University. As a principal investigator at Massachusetts General Hospital and associate professor at Harvard Medical School, he directed the work of PhD students, post-doctoral fellows, residents and visiting scientists.