Mesosil has developed a proprietary platform technology to manufacture responsive silica-based biomaterials that can be incorporated as slow-release and long-lasting antimicrobial additives into biomedical devices. Current treatment failure leads to provider-patient churn, incurring additional costs for patients and doctors and increasing the incidence of inflammation and pain in patients. Mesosil biomaterials enhance the longevity of dental treatments beyond currently available materials. The additives developed by Mesosil have been tested in consumable dental devices (i.e., dental adhesives, cement, filling materials) used to treat cavities, demonstrating their long-lasting antibacterial action. Mesosil’s additives can also be used in other semi-/permanent medical devices (i.e., catheters, implant coatings, orthopedic cement).