Tilebox is a midstream distributed computing software purpose built for space data. It provides the tooling for software developers to easily compute as close as possible to data, minimizing data transfer costs and latency. With Tilebox, any data analyst can develop scalable, distributed and mission-specific data processing pipelines at scale. Filling the gap between the upstream and the downstream; from streamlined data management to orchestrating distributed workflows across infrastructure and seamlessly integrating in-orbit processing capabilities, Tilebox radically improves how satellite operators and data companies work with space data, empowering them to create innovative data products that benefit society. Tilebox advances the ‘payload-to-platform’ value chain, while protecting data sovereignty, algorithmic autonomy, and security.