Unravel Biosciences

Unravel Biosciences has developed a vertically integrated computational platform to improve drug discovery. Instead of classic pharma, which takes a target of interest and develops drugs to bind that specific target, Unravel’s platform screens many drugs in parallel for their real-world impact (e.g., the complete gene expression profiles and resulting physiological changes), reversing this process to identify the likely target(s) a drug is interacting with. Unravel’s integrated system, a combination of cell culture, a scalable CRISPR-based disease model (tadpoles), and proprietary computational software, transforms the linear process of drug discovery into an iterative loop where the outputs are continually refined.